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Formula: C21H21BrN2O3
ROC-325 antagonizes renal cell carcinoma (RCC) growth and survival in an ATG5/7-dependent manner
A bis-Benzylidine Piperidone Targeting Proteasome Ubiquitin Receptor RPN13/ADRM1 as a Therapy for Cancer
2014 Jun 20
phosphatidylinositol hydrolysis assays
AUY-922 - CAS# 747412-49-3 size:2mg solid Formula: C21H21BrN2O3AUY 922, also known as Luminespib, NVP AUY922, VER52296, CAS No. 747412 49 3, is a derivative of 4, 5 diarylisoxazole and a third generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY 922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins; the inhibition of cell proliferation; and the elevation of heat shock
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