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[1-3] In a type II collagen-induced arthritis (CIA) mice model
3-benzodioxol-5-yl)-2-[N-(5-chloro-2-methoxyphenyl)benzenesulfonamido]acetamide
suggesting rolapitant is a viable clinical candidate for this indication
PubMed Central PMCID: PMC4101245
It was also shown to have affinity for 5-HT2B and 5-HT1A receptors with IC50 of 9
5-Ethynyluridine paphorine [1-3] In a type II5 Ethynyluridine is used to help detect RNA synthesis in cells by its biosynthetic incorporation into newly transcribed RNA. Product information CAS Number: 69075 42 9 Molecular Weight: 268. 22 Formula: C11H12N2O6 Chemical Name: 1 ((2R, 3R, 4S, 5R) 3, 4 Dihydroxy 5 (hydroxymethyl)tetrahydrofuran 2 yl) 5 ethynylpyrimidine 2, 4(1H, 3H) dione Smiles: C#CC1=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)NC1=O InChiKey: QCWBIPKYTBFWHH FDDDBJFASA N InChi:
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