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PMCID: PMC6973588
5% propylene glycol
Hesperidin and methyl hesperidin reduce TNF-alpha-induced VCAM-1 expression through inhibiting the phosphorylation of Akt and PKC
MDA-MB-453 and MDA-MB-231 cell lines with an IC50 close to 100 μM
also known as KU-57788
Picroside II xamethonium Bromide PMCID: PMC6973588Picroside II, an iridoid compound extracted from Picrorhiza, exhibits anti inflammatory and anti apoptotic activities. picroside II alleviates the inflammatory response in sepsis and enhances immune function by inhibiting the activation of NLRP3 inflammasome and NF B pathways. Picroside II is an antioxidant, exhibits a significant neuroprotective effect through reducing ROS production and protects the blood brain barrier (BBB) after cerebral ischemia