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C7H17NO5/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13
(±)-McN 5652 x (CX-516) C7H17NO5/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13() McN 5652 is a highly potent inhibitor of serotonin (5 HT, 5 hydroxytryptamine) uptake with a Ki value of approximately 0. 6 nM in rat brain synaptosomes in vitro and an ED50 value of approximately 2 mg kg p. o. ex vivo . 5 HT is a monoaminergic neurotransmitter to modulate numerous sensory, behavioural processes and motor in the mammalian nervous system . There are at least three main groups of 5 HT receptor: 5 HT1, 5 HT2, and 5 HT3. Each group is
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