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A single treatment with GK921 almost completely reduced tumor growth by stabilizing p53 in the ACHN and CAKI-1 preclinical xenograft tumor models
At either 1 or 10 μM
InChi: InChI=1S/C11H8Cl2O3/c12-8-2-1-5(3-9(8)13)10(14)6-4-7(6)11(15)16/h1-3
In H-69 xenografts
Chemical Name: 1-[(3
Stachydrine Catalog No.:M15001-2 A single treatment with GK921Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF B signal pathway. Product information CAS Number: 471 87 4 Molecular Weight: 143. 18 Formula: C7H13NO2 Chemical Name: (2S) 1,1 dimethylpyrrolidin 1 ium 2 carboxylate Smiles: C[N+]1(C)CCC[C@H]1C([O ])=O InChiKey: CMUNUTVVOOHQPW LURJTMIESA N InChi: InChI=1S C7H13NO2 c1 8(2)5 3 4
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