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Contraindications for VAC therapy include: Malignancy of wound Presence of necrotic/ devitalised tissue in wound bed Untreated osteomyelitis Unexplored and high output fistulas Ischaemia/ absence of blood supply Additional resources How to apply a dressing to a wound or skin tear Wound dressings downloadable leaflet (PDF) Weve created a handy downloadable leaflet of the key information on this page so you can easily print it out for personal reference or to hand to a patient or healthcare professional